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Veitia Lab – The forkhead DNA-binding domain binds specific G2-rich RNA sequences

Le domaine forkhead de liaison à l’ADN reconnait également une séquence d’ARN riche en GG.   Cette étude, publiée dans Nucleic Acids Research, résulte d’une collaboration entre les équipes de Reiner A. Veitia (directeur de l’Institut de Biologie Francois Jacob et Professeur à l’Université Paris Cité) et l’équipe de Frédéric Ducongé (CEA-MIRCen, UMR CNRS 9199, Université…

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Ladoux / Mège Lab – A mechanosensitive caveolae-invadosome interplay drives matrix remodelling for cancer cell invasion

L'équipe Ladoux / Mège a récemment contribué à la publication d'un nouvel article dans Nature Cell biology : A mechanosensitive caveolae–invadosome interplay drives matrix remodelling for cancer cell invasion Résumé : Invadosomes and caveolae are mechanosensitive structures that are implicated in metastasis. Here, we describe a unique juxtaposition of caveola clusters and matrix degradative invadosomes at…

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Camadro Lab – The five pillars of computational reproducibility: bioinformatics and beyond

L'équipe Camadro a récemment contribué à la publication d'un nouvel article dans Briefing in Bioinformatics : The five pillars of computational reproducibility: bioinformatics and beyond   Résumé : Computational reproducibility is a simple premise in theory, but is difficult to achieve in practice. Building upon past efforts and proposals to maximize reproducibility and rigor in bioinformatics, we present a…

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Courtier Lab – The loci of insect phenotypic evolution

L'équipe Courtier a récemment publié un nouvel article dans Current Opinion in Insect Science : The loci of insect phenotypic evolution   Résumé : Insects are important elements of terrestrial ecosystems because they pollinate plants, destroy crops, transmit diseases to livestock and humans, and are important components of food chains. Here, I used Gephebase, a manually curated database…

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Grange/Geigl Lab – Genome sequences of 36-37,000 year-old modern humans at Buran-Kaya III in Crimea

L'équipe Grange/Geigl a publié un nouvel article dans Nature Ecology and Evolution :  Genome sequences of 36-37,000 year-old modern humans at Buran-Kaya III in Crimea Deux génomes de 36-37 000 ans de Crimée éclairent les premières implantations réussies des Humains modernes en Europe et l’émergence du Gravettien L’implantation des Humains en Eurasie après leur sortie d’Afrique fut un…

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Gazave Lab – Transcriptomic landscape of posterior regeneration in the annelid Platynereis dumerilii

L'équipe Gazave a récemment publié un nouvel article dans BMC Genomics : Transcriptomic landscape of posterior regeneration in the annelid Platynereis dumerilii Résumé : Background Restorative regeneration, the capacity to reform a lost body part following amputation or injury, is an important and still poorly understood process in animals. Annelids, or segmented worms, show amazing regenerative capabilities,…

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Palancade Lab – A R-loop sensing pathway mediates the relocation of transcribed genes to nuclear pore complexes

L'équipe Palancade a récemment publié un nouvel article dans Nature communications : A R-loop sensing pathway mediates the relocation of transcribed genes to nuclear pore complexes   Résumé : Nuclear pore complexes (NPCs) have increasingly recognized interactions with the genome, as exemplified in yeast, where they bind transcribed or damaged chromatin. By combining genome-wide approaches with live…

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Ladoux /Mège Lab – Hexanematic crossover in epithelial monolayers depends on cell adhesion and cell density

L'équipe Ladoux/Mège a contribué à la publication d'un article dans Nature Communications :  Hexanematic crossover in epithelial monolayers depends on cell adhesion and cell density Résumé : Changes in tissue geometry during developmental processes are associated with collective migration of cells. Recent experimental and numerical results suggest that these changes could leverage on the coexistence of nematic…

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Conduit Lab & Guichet Lab – Multifaceted modes of γ-tubulin complex recruitment and microtubule nucleation at mitotic centrosomes

L'équipe Conduit et l'équipe Guichet ont récemment publié dans Journal of Cell Biology : Multifaceted modes of γ-tubulin complex recruitment and microtubule nucleation at mitotic centrosomes Résumé : Microtubule nucleation is mediated by γ-tubulin ring complexes (γ-TuRCs). In most eukaryotes, a GCP4/5/4/6 “core” complex promotes γ-tubulin small complex (γ-TuSC) association to generate cytosolic γ-TuRCs. Unlike γ-TuSCs, however,…

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