La plateforme ProtéoSeine et l'équipe Léon ont publié une nouvelle publication dans BMC Microbiology : Candida albicans cells exhibit media specific proteomic profiles during induction of filamentation Résumé : Candida albicans is an opportunist pathogen responsible for a broad spectrum of infections, from superficial mycosis to the systemic disease candidiasis. C. albicans has various morphological forms, including unicellular budding yeasts,…

L’équipe Grange / Geigl a publié un nouvel article dans Molecular biology and evolution : The Population History of Domestic Sheep Revealed by Paleogenomes   Les moutons ont été l'un des premiers animaux à être domestiqués. L'analyse des génomes extraits d'ossements de moutons archéologiques conservés dans des sites néolithiques a permis à Kaptan et à ses collègues de démontrer que les…

L'équipe Minc a contribué à la publication d'un nouvel article dans Biophysical Journal : A physical model for M1-mediated influenza A virus assembly   Résumé : Influenza A virus particles assemble at the plasma membrane of infected cells. During assembly all components of the virus come together in a coordinated manner to deform the membrane into a…

L'équipe Duharcourt a publié un nouvel article dans Nucleic Acids Research : The PIWI-interacting protein Gtsf1 controls the selective degradation of small RNAs in Paramecium   Résumé : Ciliates undergo developmentally programmed genome elimination, in which small RNAs direct the removal of transposable elements (TEs) during the development of the somatic nucleus. Twenty-five nucleotide scanRNAs (scnRNAs) are produced from…

L'équipe Romet-Lemonne/Jégou a contribué à la publication d'un nouvel article dans PNAS : HIV-1 budding requires cortical actin disassembly by the oxidoreductase MICAL1   Résumé : Many enveloped viruses bud from the plasma membrane that is tightly associated with a dense and thick actin cortex. This actin network represents a significant challenge for membrane deformation and scission, and…

L'équipe Minc a publié un article de méthode dans Methods in Molecular Biology :  Analysis of Cell Wall Mechanics in Fission Yeast   Résumé : The growth and shape of fungal cells, such as fission yeast, are strongly constrained by the mechanics of their cell wall (CW). The cell wall encases the plasma membrane and defines instantaneous cell shapes…

L'équipe Dumont a contribué à un article publié dans microPublication Biology : Cell type-specific regulation by different cytokinetic pathways in the early embryo Résumé : Cytokinesis, the physical division of one cell into two, is typically assumed to use the same molecular process across animal cells. However, regulation of cell division can vary significantly among different cell…

La plateforme ProtéoSeine a contribué à la publication d'un nouvel article dans ACS Chemical Biology : Bioorthogonal Monomycolate of Trehalose Disclosed the O-Mycoloylation of Mycoloyltransferases and Other Cell Envelope Proteins in C. glutamicum   Résumé : Protein mycoloylation is a recently identified unusual post-translational modification (PTM) exclusively observed in Mycobacteriales, an order of bacteria that includes several human pathogens.…

L'équipe Courtier a publié un nouvel article dans Evolutionary Biology : A scenario for an evolutionary selection of ageing Résumé : Signs of ageing become apparent only late in life, after organismal development is finalized. Ageing, most notably, decreases an individual’s fitness. As such, it is most commonly perceived as a non-adaptive force of evolution and…