L'équipe Camadro (en collaboration avec ProteoSeine, Dumont Lab et Ladoux/Mège Lab) vient de publier un nouvel article dans Journal of Proteome Research : Extending the Range of SLIM-Labeling Applications: From Human Cell Lines in Culture to Caenorhabditis elegans Whole-Organism Labeling   Abstract The simple light isotope metabolic-labeling technique relies on the in vivo biosynthesis of amino acids from U-[12C]-labeled molecules…

L'équipe Minc vient de publier un nouvel article dans PNAS :   Size- and position-dependent cytoplasm viscoelasticity through hydrodynamic interactions with the cell surface   Abstract Many studies of cytoplasm rheology have focused on small components in the submicrometer scale. However, the cytoplasm also baths large organelles like nuclei, microtubule asters, or spindles that often take significant portions of…

L'équipe Dumont vient de publier un nouvel article dans eLife : Synergistic stabilization of microtubules by BUB-1, HCP-1 and CLS-2 controls microtubule pausing and meiotic spindle assembly   Abstract During cell division, chromosome segregation is orchestrated by a microtubule-based spindle. Interaction between spindle microtubules and kinetochores is central to the bi-orientation of chromosomes. Initially dynamic to allow…

L'équipe Romet-Lemonne/Jégou vient de publier dans Biophysical Journal : (ABSTRACT  VOLUME 122, ISSUE 3, SUPPLEMENT 1, 166A-167A,  FEBRUARY 10, 2023)   The Arp2/3 complex contributes to the regeneration of branched actin filament networks   Actin filaments are one of the indispensable components of almost all cell types. These semi-flexible filaments constitute an important part of the cytoskeleton and give…

DNA Modification Patterns Filtering and Analysis Using DNAModAnnot Hardy, A., Duharcourt, S., Defrance, M. (2023). DNA Modification Patterns Filtering and Analysis Using DNAModAnnot. In: H. Oliveira, P. (eds) Computational Epigenomics and Epitranscriptomics. Methods in Molecular Biology, vol 2624. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-2962-8_7 Abstract Mapping DNA modifications at the base resolution is now possible at…