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Romet-Lemonne/Jegou Lab – Regulation of branched versus linear Arp2/3-generated actin filaments

L’équipe Romet-Lemonne/Jegou vient de publier un nouvel article dans the EMBO Journal. Regulation of branched versus linear Arp2/3-generated actin filaments Abstract Activation of the Arp2/3 complex by VCA-motif-bearing actin nucleation-promoting factors results in the formation of “daughter” actin filaments branching off the sides of pre-existing “mother” filaments. Alternatively, when stimulated by SPIN90, Arp2/3 directly nucleates “linear” actin…

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Séminaire IJM – Stéphane Peyrégne – 26/05/2023

  Invité par l'équipe Grange/Geigl, Stéphane Peréygne, donnera un séminaire sur le thème :   "Reconstructing the evolutionary and population history of archaic and modern humans." Computational Ancient Genomics (Janet Kelso) The group develops and applies computational approaches for the analysis of ancient and modern human genomes. Ancient genomes In the last 10 years ongoing work in the Genetics…

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Cytoskeleton Club – 17/05/2023

La prochaine réunion du Cytoskeleton Club aura lieu mercredi 17 mai à l’Institut Pasteur (Auditorium Francois Jacob). Trois orateurs seront présents : Murielle Serres (post-doc, A. Echard, Institut Pasteur) va présenter MiniBAR a dual Rac and Rab effector that controls cilia length and left-right asymmetry in vivo Béatrice Benoit (C. Poüs Lab, Faculté de Pharmacie,…

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Greenberg Lab – Conservation and divergence of canonical and non-canonical imprinting in murids

L'équipe Greenberg vient de publier dans Genome Biology. Conservation and divergence of canonical and non-canonical imprinting in murids Abstract Background Genomic imprinting affects gene expression in a parent-of-origin manner and has a profound impact on complex traits including growth and behavior. While the rat is widely used to model human pathophysiology, few imprinted genes have been…

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Séminaire IJM – Ozren Bogdanovic – 12/05/2023

Invité par Maxim Greenberg, Ozren Bogdanovic (Andalusian Centre for Developmental Biology, Seville, Spain) donnera un séminaire IJM le vendredi 12 mai 2023 sur le thème : Evolutionary conservation and divergence of embryonic DNA methylome remodelling in fishes Methylation of cytosines is the most abundant DNA modification in vertebrates that plays crucial roles in cellular differentiation and…

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Séminaire IJM – Antoine Molaro – 28/04/2023

  Invité par le Young Scientist Club, Antoine Molaro (Université de Clermont Auvergne, France) donnera un séminaire IJM le 28 avril sur le thème : Unusual Histones Mediate (epi)Génétic Conflicts during Reproduction Foreword I am broadly interested in understanding the function of the germline epigenome. In mammals, the germline epigenome is key to the inheritance of genetic and…

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Cytoskeleton Club – 19/04/2023

La prochaine réunion du Cytoskeleton Club aura lieu mercredi 19 avril à l'Institut Curie (Amphithéâtre C.Burg). Trois orateurs seront présents : Sandra Carvalho (PhD student, Guichet lab, IJM) va présenter : "Function and dynamics of Actin cytoskeleton in 3D cell intercalation during development" Nathalie Delgehyr (Researcher, Nathalie Spassky lab, IBENS) va présenter : "Actin-based deformations of the cell nucleus trigger neural stem cell progenitor differentiation" …

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Séminaire IJM – Diyendo Massilani – 18/04/2023

Invité par Eva-Maria Geigl et Thierry Grange, Diyendo Massilani va donner un séminaire IJM le mardi 18 avril 2023 sur le thème : "Genomic analysis of a 34,000-year-old human individual from Mongolia" We investigate the evolutionary history of modern and extinct human populations using ancient DNA. Our focus is to retrieve and sequence DNA from archaeological…

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Camadro Lab – Extending the Range of SLIM-Labeling Applications: From Human Cell Lines in Culture to Caenorhabditis elegans Whole-Organism Labeling

L'équipe Camadro (en collaboration avec ProteoSeine, Dumont Lab et Ladoux/Mège Lab) vient de publier un nouvel article dans Journal of Proteome Research : Extending the Range of SLIM-Labeling Applications: From Human Cell Lines in Culture to Caenorhabditis elegans Whole-Organism Labeling   Abstract The simple light isotope metabolic-labeling technique relies on the in vivo biosynthesis of amino acids from U-[12C]-labeled molecules…

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