The Grange/Geigl Lab published a new article in Science Advances: Arrival of steppe-ancestry in the north of France observed in real-time explains the shaping of the European genome   The last major migratory wave that shaped the European genome was that of the populations from the steppes north of the Black Sea ~5,000 years. These steppe pastoralists…

Researchers at the Institut Jacques Monod have published a collaborative study ( preprint) on the conditions of use of various GFP and RFP for the direct detection of fluorescence in gels: Direct observation of fluorescent proteins in gels: a rapid, cost-efficient and quantitative alternative to immunoblotting   Abstract: The discovery of Green Fluorescent Protein (GFP) and its derivatives…

The ImagoSeine platform contributed to the publication of a new article in Circulation: CAVIN1-Mediated hERG Dynamics: A Novel Mechanism Underlying the Interindividual Variability in Drug-Induced Long QT   Abstract: BACKGROUND: Drug-induced QT prolongation (diLQT) is a feared side effect that could expose susceptible individuals to fatal arrhythmias. The occurrence of diLQT is primarily attributed to unintended drug interactions…

The Dumont Lab contributed to the publication of a new article in Molecular Biology of Cell: Germ fate determinants protect germ precursor cell division by reducing septin and anillin levels at the cell division plane   Abstract: Animal cell cytokinesis, or the physical division of one cell into two, is thought to be driven by constriction of an…

The Ribes Lab contributed to the publication of a review in Biomedicines: Non-Mammalian Models for Understanding Neurological Defects in RASopathies   Abstract: RASopathies, a group of neurodevelopmental congenital disorders stemming from mutations in the RAS/MAPK pathway, present a unique opportunity to delve into the intricacies of complex neurological disorders. Afflicting approximately one in a thousand newborns, RASopathies manifest…