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Doye Lab – Y-complex nucleoporins independently contribute to nuclear pore assembly and gene regulation in neuronal progenitors

The Doye Lab's new article made the cover and the highlight of Journal of Cell Science : Y-complex nucleoporins independently contribute to nuclear pore assembly and gene regulation in neuronal progenitors Abstract: Besides assembling nuclear pore complexes, the conduits of nuclear transport, many nucleoporins also contribute to chromatin organization and gene expression, with critical roles in development and…

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EMBO member election – Dr. Sandra Duharcourt and Dr. Katja Wassmann

Dr. Sandra Duharcourt and Dr. Katja Wassmann The Institut Jacques Monod is very proud to announce the election of Dr.Sandra Duharcourt and Dr.Katja Wassmann as members of the European Molecular Biology Organization (EMBO) community. Congratulations! EMBO is an international organization of life science researchers with over 1900 members elected by their peers. EMBO's main objectives are…

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Gazave Lab – On the hormonal control of posterior regeneration in the annelid Platynereis dumerilii

The Gazave lab recently published in Journal of Experimental Zoology part B: Molecular and developmental evolution : On the hormonal control of posterior regeneration in the annelid Platynereis dumerilii Abstract: Regeneration is the process by which many animals are able to restore lost or injured body parts. After amputation of the posterior part of its body, the annelid Platynereis dumerilii is…

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Duharcourt Lab – Dynamics of gene loss following ancient whole-genome duplication in the cryptic Paramecium complex

The Duharcourt Lab just published in Molecular Biology and Evolution : Dynamics of gene loss following ancient whole-genome duplication in the cryptic Paramecium complex Abstract: Whole-genome duplications (WGDs) have shaped the gene repertoire of many eukaryotic lineages. The redundancy created by WGDs typically results in a phase of massive gene loss. However, some WGD-derived paralogs are maintained over long…

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Courtier Lab – Analysis of the genetic loci of pigment pattern evolution in vertebrates

Courtier's Lab just published in Biological reviews : Analysis of the genetic loci of pigment pattern evolution in vertebrates Vertebrate pigmentation patterns are amongst the best characterised model systems for studying the genetic basis of adaptive evolution. The wealth of available data on the genetic basis for pigmentation evolution allows for analysis of trends and quantitative…

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Guichet Lab – Basal stem cell progeny establish their apical surface in a junctional niche during turnover of an adult barrier epithelium

The Guichet Lab just published in Nature cell Biology : Basal stem cell progeny establish their apical surface in a junctional niche during turnover of an adult barrier epithelium Barrier epithelial organs face the constant challenge of sealing the interior body from the external environment while simultaneously replacing the cells that contact this environment. New replacement…

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Romet-Lemonne/Jegou Lab – Regulation of branched versus linear Arp2/3-generated actin filaments

The Romet-Lemonne/Jegou's Team has just published a new paper in the EMBO Journal. Regulation of branched versus linear Arp2/3-generated actin filaments Abstract Activation of the Arp2/3 complex by VCA-motif-bearing actin nucleation-promoting factors results in the formation of “daughter” actin filaments branching off the sides of pre-existing “mother” filaments. Alternatively, when stimulated by SPIN90, Arp2/3 directly nucleates “linear”…

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Greenberg Lab – Conservation and divergence of canonical and non-canonical imprinting in murids

The Greenberg's team has just published a paper in Genome Biology. Conservation and divergence of canonical and non-canonical imprinting in murids Abstract Background Genomic imprinting affects gene expression in a parent-of-origin manner and has a profound impact on complex traits including growth and behavior. While the rat is widely used to model human pathophysiology, few imprinted…

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