The Camadro Lab just published in  Biochemistry and Molecular Biology Education : A field guide for implementing a flipped classroom Abstract : The way flipped classrooms are perceived and even practiced by teachers is sometimes approximate. For instance, while the Covid-19 pandemic has pushed many universities to adopt distance learning, flipped classrooms have often been mentioned as…

Courtier's Lab just published in Biological reviews : Analysis of the genetic loci of pigment pattern evolution in vertebrates Vertebrate pigmentation patterns are amongst the best characterised model systems for studying the genetic basis of adaptive evolution. The wealth of available data on the genetic basis for pigmentation evolution allows for analysis of trends and quantitative…

The Guichet Lab just published in Nature cell Biology : Basal stem cell progeny establish their apical surface in a junctional niche during turnover of an adult barrier epithelium Barrier epithelial organs face the constant challenge of sealing the interior body from the external environment while simultaneously replacing the cells that contact this environment. New replacement…

The Wassmann team has just published a paper in Med/Sci ( Paris) : Cyclin B3: Locking female meiosis to await fertilization  

The Romet-Lemonne/Jegou's Team has just published a new paper in the EMBO Journal. Regulation of branched versus linear Arp2/3-generated actin filaments Abstract Activation of the Arp2/3 complex by VCA-motif-bearing actin nucleation-promoting factors results in the formation of “daughter” actin filaments branching off the sides of pre-existing “mother” filaments. Alternatively, when stimulated by SPIN90, Arp2/3 directly nucleates “linear”…

The Greenberg's team has just published a paper in Genome Biology. Conservation and divergence of canonical and non-canonical imprinting in murids Abstract Background Genomic imprinting affects gene expression in a parent-of-origin manner and has a profound impact on complex traits including growth and behavior. While the rat is widely used to model human pathophysiology, few imprinted…

The Camadro team has just published in Journal of Proteome Research a new paper (in collaboration with ProteoSeine, Dumont Lab and Ladoux/Mège Lab): Extending the Range of SLIM-Labeling Applications: From Human Cell Lines in Culture to Caenorhabditis elegans Whole-Organism Labeling   Abstract The simple light isotope metabolic-labeling technique relies on the in vivo biosynthesis of amino acids from U-[12C]-labeled molecules…

The Minc team has just published a new paper in PNAS:   Size- and position-dependent cytoplasm viscoelasticity through hydrodynamic interactions with the cell surface   Abstract Many studies of cytoplasm rheology have focused on small components in the submicrometer scale. However, the cytoplasm also baths large organelles like nuclei, microtubule asters, or spindles that often take significant portions of…

The Dumont team has just published a new paper in eLife: Synergistic stabilization of microtubules by BUB-1, HCP-1 and CLS-2 controls microtubule pausing and meiotic spindle assembly   Abstract During cell division, chromosome segregation is orchestrated by a microtubule-based spindle. Interaction between spindle microtubules and kinetochores is central to the bi-orientation of chromosomes. Initially dynamic to allow…

L'équipe Romet-Lemonne/Jégou has just published a new article in Biophysical Journal : (ABSTRACT  VOLUME 122, ISSUE 3, SUPPLEMENT 1, 166A-167A,  FEBRUARY 10, 2023)   The Arp2/3 complex contributes to the regeneration of branched actin filament networks   Actin filaments are one of the indispensable components of almost all cell types. These semi-flexible filaments constitute an important part of the…