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Duharcourt Lab – DNA Modification Patterns Filtering and Analysis Using DNAModAnnot

DNA Modification Patterns Filtering and Analysis Using DNAModAnnot Hardy, A., Duharcourt, S., Defrance, M. (2023). DNA Modification Patterns Filtering and Analysis Using DNAModAnnot. In: H. Oliveira, P. (eds) Computational Epigenomics and Epitranscriptomics. Methods in Molecular Biology, vol 2624. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-2962-8_7 Abstract Mapping DNA modifications at the base resolution is now possible…

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IJM Seminar – Joel Dacks – 14/04/2023

Invited by Cathy Jackson, Joel Dacks (Division of Infectious Diseases, Department of Medicine, University of Alberta, Edmonton, Canada) will give a seminar entitled: Unsuspected components and ancient origins of the eukaryotic membrane-trafficking system   Biography I am currently an Honorary Professor in the Department of Genetics, Evolution and Environment, linked with the Centre for Life’s Origins and…

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Postdoc to study microtubule regulation (Conduit Lab)

The Conduit lab studies how microtubule nucleation is regulated in a cell-specific manner to allow different cells to form their specialised microtubule arrays. Regulation of γ-TuRC activation Microtubules are essential cell components linked to many human pathologies. They are nucleated by muti-protein gamma-tubulin ring complexes (γ-TuRCs), which are themselves potential targets for cancer therapy. Microtubule nucleation needs to…

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The “Cell Adhesion and Mechanics” Team is recruiting an engineer

Informations générales Lieu de travail : PARIS 13 Date de publication : mercredi 1 février 2023 Type de contrat : CDD Technique/Administratif Durée du contrat : 24 mois Date d'embauche prévue : 20 mars 2023 Quotité de travail : Temps complet Rémunération : entre 2 280 € bruts (exp.< 3 ans) et 2 560 € bruts (exp. entre 5 et 9 ans) Niveau d'études souhaité : Bac+3 Expérience souhaitée…

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IJM Seminar – Matteo Rauzi – 07/04/2023

Invited by Nicolas Minc, Matteo Rauzi (Université Côte d’Azur, CNRS, Inserm, iBV, Nice, France) will give an IJM Seminar entitled: Composite morphogenesis: how can a tissue fold and extend at the same time During embryo development, epithelia can undergo different shape transformations. While these changes can be sequential, and thus driven by specific sequential cellular mechanisms,…

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IJM Seminar – Grégory Giannone – 31/03/2023

Invited by the Romet-Lemonne/Jégou Team, Grégory Giannone will give a seminar entitled : "Deciphering the spatiotemporal and mechanical regulation of integrin and actin regulators at the nanoscale" Giannone Lab: Cells have the ability to adjust their adhesive and cytoskeletal organizations according to changes in the biochemical and physical nature of their surroundings. In return, by adhering…

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IJM Seminar – Stéphane Vassilopoulos – 10/03/2023

Invited by René-Marc Mège, Stéphane Vassilopoulos (Sorbonne Université, INSERM, Institute of Myology, Centre of Research in Myology) will give an IJM Seminar entitled: Mechanosensitive clathrin platforms regulate YAP/TAZ signaling   Our lab works on the role of membrane trafficking mechanisms in physiology and their involvement in genetic diseases. The group is part of  the Institute of…

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Minc Lab – Cell wall dynamics stabilize tip growth in a filamentous fungus

The Minc team has just published a new paper in  PLOS Biology Cell wall dynamics stabilize tip growth in a filamentous fungus   Abstract Hyphal tip growth allows filamentous fungi to colonize space, reproduce, or infect. It features remarkable morphogenetic plasticity including unusually fast elongation rates, tip turning, branching, or bulging. These shape changes are all driven from…

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Veitia Lab – The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors

The Veitia team has just published a new paper in Cancer Research : The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors   Abstract Adult-type granulosa cell tumors (AGCT) are the most common type of malignant ovarian sex cord–stromal tumors. Most AGCTs carry the somatic variant c.402C>G (p.C134W) affecting the transcription factor FOXL2.…

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IJM Seminar – Prisca Liberali – 28/02/2023

Invited by the Ladoux/Mège team, Prisca Liberali (Senior Group Leader, Friedrich Miescher Institute for Biomedical Research -FMI) will an IJM seminar entitled: Design principles of tissue organization   SELF-ORGANISATION DURING COLLECTIVE BEHAVIOUR Robust experimental model systems have recently been developed from adult or induced pluripotent stem cells that self-organise into organoid structures in vitro. In particular, intestinal organoids…

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