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Veitia Lab – The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors

The Veitia team has just published a new paper in Cancer Research : The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors   Abstract Adult-type granulosa cell tumors (AGCT) are the most common type of malignant ovarian sex cord–stromal tumors. Most AGCTs carry the somatic variant c.402C>G (p.C134W) affecting the transcription factor FOXL2.…

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IJM Seminar – Prisca Liberali – 28/02/2023

Invited by the Ladoux/Mège team, Prisca Liberali (Senior Group Leader, Friedrich Miescher Institute for Biomedical Research -FMI) will an IJM seminar entitled: Design principles of tissue organization   SELF-ORGANISATION DURING COLLECTIVE BEHAVIOUR Robust experimental model systems have recently been developed from adult or induced pluripotent stem cells that self-organise into organoid structures in vitro. In particular, intestinal organoids…

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Cytoskeleton Club – 15/02/2023

We will have our Cytoskeleton Meeting Wednesday 15th of February at 9.30 am at the Pasteur Institute (Auditorium F. Jacob), side 28 rue du Dr Roux 75015 Paris.   Akila Merah Yagoubat (post-doc, Paul Conduit lab, Institut Jacques Monod) will tell us about: Asymmetric microtubule nucleation from Somatic Golgi of Drosophila neuons Jean de Seze (PhD student, Mathieu Coppey lab, Institut Curie). will…

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Proteoseine – Capillary liquid chromatography coupled with mass spectrometry for analysis of nanogram protein quantities on a wide-pore superficially porous particle column in top-down proteomics

The Protoseine Facility has just published a new paper in  Journal of Chromatography B : Capillary liquid chromatography coupled with mass spectrometry for analysis of nanogram protein quantities on a wide-pore superficially porous particle column in top-down proteomics   Abstract In top-down proteomics experiments, intact protein ions are subjected to gas-phase fragmentation for MS analysis without…

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Grange/Geigl Lab – Analysis of Ancient Microbial DNA

The Grange/Geigl team recently published a book chapter i Microbial Environmental Genomics (Part of the Methods in Molecular Biology book series (MIMB,volume 2605) Analysis of Ancient Microbial DNA Abstract The development of next-generation sequencing has led to a breakthrough in the analysis of ancient genomes, and the subsequent genomic analyses of ancient human skeletal remains have…

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IJM Seminar – Susana Godinho – 24/01/2023

Invited by Paul Conduit, Susana Godinho (Barts Cancer Institute, London, UK) will give an IJM Seminar entitled : Microtubules as mediators of stress responses and repair Research Cancer cells often contain extra centrosomes. The centrosome is the main microtubule-organizing centre in animal cells, an essential component of the cytoskeleton. In normal cells, centrosome number is tightly regulated,…

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Cytoskeleton Club – 18/01/2023

The next Cytoskeleton Club session will be held on January 18th at the Institut Curie (Amphi Burg) with : Foad Ghasemi (PhD Student, Romet-Lemonne / Jégou Lab - Institut Jacques Monod) : "New surprises from an old friend: Arp2/3, nucleation of actin filament branches and beyond" Aurore Maciejewski (PhD Student, Jaulin Lab - Institut…

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IJM Seminar – Antoine Hocher – 06/01/2023

Invited by Sandra Duharcourt, Antoine Hocher (MRC, London Institute of Medical Sciences) will give on January 6th a seminar entitled : Histones, beyond eukaryotes   Research Our goal is to understand how what is happening inside the cell biases the incidence of mutations, affects their persistence, and, ultimately, shapes patterns of natural variation within and between species. Some…

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