The Conduit Lab published a new review in Nature Structural & Molecular Biology:
Cryo-EM structures of γ-TuRC reveal molecular insights into microtubule nucleation
Abstract:
Microtubules within cells often have 13 protofilaments but are nucleated by multi-protein y-TuRCs complexes that display 14 γ-tubulin molecules. High-resolution cryo-EM structures of γ-TuRCs after nucleation show that these γ-TuRCs ‘close’ during nucleation…
The Gazave published a new article in Development:
Variations in cell plasticity and proliferation underlie distinct modes of regeneration along the antero-posterior axis in the annelid Platynereis
Abstract:
The capacity to regenerate lost tissues varies significantly among animals. Some phyla, such as the annelids, display substantial regenerating abilities, although little is known about the cellular mechanisms…
The Konstantinides Lab published a new article in CSH Perspectives:
Neuronal Circuit Evolution: From Development to Structure and Adaptive Significance
Abstract:
Neuronal circuits represent the functional units of the brain. Understanding how the circuits are generated to perform computations will help us understand how the brain functions. Nevertheless, neuronal circuits are not engineered, but have formed through…
The Grange/Geigl Lab contributed to the publication of a new article in Molecular Ecology:
The first complete genome of the extinct European wild ass (Equus hemionus hydruntinus)
Abstract:
A fruitful collaboration of the Grange/Geigl team with the Compevo team led by Mehmet Somel at METU in Ankara http://compevo.bio.metu.edu.tr/ within the EU-funded H2020 Twining program Neomatrix https://neomatrix.metu.edu.tr/ has…
The Grange/Geigl Lab published a new article in Science Advances:
Arrival of steppe-ancestry in the north of France observed in real-time explains the shaping of the European genome
The last major migratory wave that shaped the European genome was that of the populations from the steppes north of the Black Sea ~5,000 years. These steppe pastoralists…
Invited by the Courtier, Vincent Laudet (Eco-Evo-Devo Unit, Okinawa Institute of Science and Technology, Japan / Institute of Cellular and Organismic Biology, Academia Sinica, Taiwan. CNRS IRL 2028 “Eco-Evo-Devo of Coral Reef Fish Life Cycle” (EARLY) ) will present an Institut Jacques Monod Seminar on the theme:
Clownfishes: New models for Eco-Evo-Devo
Abstract:
Clownfishes are becoming relevant…
The next Cytoskeleton Club meeting will take place on Wednesday, June 19th 2024 at the Institut Curie (amphitheater Burg, 12 rue Lhomong 75005 Paris) :
Riham Salame (PhD student, Renata Basto Lab, Institut Curie) will present "Identification of the mechanisms underlying centrosome elimination and microtubule cytoskeleton reorganization in programmed polyploid cells."
Valeria Viola (PhD…
Researchers at the Institut Jacques Monod have published a collaborative study ( preprint) on the conditions of use of various GFP and RFP for the direct detection of fluorescence in gels:
Direct observation of fluorescent proteins in gels: a rapid, cost-efficient and quantitative alternative to immunoblotting
Abstract:
The discovery of Green Fluorescent Protein (GFP) and its derivatives…
The ImagoSeine contributed to the publication of a new article in Science Advances:
Altered X-chromosome inactivation predisposes to autoimmunity
Abstract:
In mammals, males and females show marked differences in immune responses. Males are globally more sensitive to infectious diseases, while females are more susceptible to systemic autoimmunity. X-chromosome inactivation (XCI), the epigenetic mechanism ensuring the silencing of…
Invited by the Konstantinides, Ezzat El-Sherif (School of Integrative Biological and Chemical Sciences, University of Texas Rio Grande Valley, Edinburg, Texas, US) will present an Institut Jacques Monod Seminar on the theme:
How enhancers translate time into space during development
Abstract:
In embryonic development, is time more important or space? Conventionally, the answer would be: Both! However,…