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Conduit Lab & Guichet Lab – Multifaceted modes of γ-tubulin complex recruitment and microtubule nucleation at mitotic centrosomes

L'équipe Conduit et l'équipe Guichet ont récemment publié dans Journal of Cell Biology : Multifaceted modes of γ-tubulin complex recruitment and microtubule nucleation at mitotic centrosomes Résumé : Microtubule nucleation is mediated by γ-tubulin ring complexes (γ-TuRCs). In most eukaryotes, a GCP4/5/4/6 “core” complex promotes γ-tubulin small complex (γ-TuSC) association to generate cytosolic γ-TuRCs. Unlike γ-TuSCs, however,…

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Azimzadeh Lab – Evolution: The ancient history of cilia assembly regulation

L'équipe Azimzadeh a récemment publié dans Current Biology : Evolution: The ancient history of cilia assembly regulation Résumé : A new study identifies a conserved regulatory mechanism for cilia assembly in the closest unicellular relatives of animals, suggesting that this mechanism was already present in a common unicellular ancestor and was repurposed during the transition to multicellularity.

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Séminaire IJM – Yoichi Shinkai – 20/10/2023

Invité par l'équipe Greenberg, Yoichi Shinkai (Chief Scientist at the Cellular Memory Laboratory, Riken, Japan) va présenter un séminaire IJM sur le thème :   Biology of Histidine Methylation Résumé : We have been using a synthetic cofactor analog of SAM, ProSeAM to analyze novel substrates of lysine methyltransferases and their biological functions. Recently, we have been using…

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Séminaire IJM – Ben Montpetit – 12/10/2023

Invité par l'équipe Palancade, Ben Montpetit (Université de Californie, Davis, USA) présentera un séminaire IJM sur le thème : RNA-binding protein (RBP) recruitment, occupancy, and stoichiometry in nuclear mRNA-protein complexes. Résumé : RNA-binding proteins (RBPs) interact with mRNA and associated factors to form supramolecular complexes called messenger ribonucleoprotein (mRNP) particles. These dynamic assemblies change to direct and…

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Cytoskeleton club – 18/10/23

La première réunion du cytoskeleton club aura lieu le mercredi 18 octobre à 9h30 à l'Institut Pasteur (salle Bordet Metchnikoff  - 25 rue du Dr Roux 75015 Paris) Pour cette première réunion : - Guillaume MONTAGNAC, (Chef de groupe du laboratoire " Endocytose, cytosquelette et migration cellulaire ", Institut Gustave Roussy) présentera : "La mécanique de la…

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Séminaire IJM – Joao Matos – 10/10/2023

Invité par l'équipe Wassmann, Joao Matos (Max Perutz Labs, University of Vienna) présentera un séminaire IJM sur le thème : Building, maintaining and discarding large macromolecular assemblies during gametogenesis The life cycle of sexually reproducing eukaryotes depends on two specialized chromosome segregation programs: mitosis and meiosis. Whereas mitosis drives cellular proliferation and the stable propagation of…

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Séminaire IJM – Ana Rita Gomes – 06/10/2023

Invitée par l'équipe Prioleau, Ana Rita Gomes (LPHI - Laboratory of Pathogens and Host Immunity, Université de Montpellier) présentera un séminaire IJM sur le thème : The genetic landscape of origins of replication in P. falciparum   A variety of origin mapping approaches have enabled genome-wide identification of origins of replication (ORI) in model organisms, but only…

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