La plateforme Protoseine vient de publier un nouvel article dans Journal of Chromatography B : Capillary liquid chromatography coupled with mass spectrometry for analysis of nanogram protein quantities on a wide-pore superficially porous particle column in top-down proteomics   Abstract In top-down proteomics experiments, intact protein ions are subjected to gas-phase fragmentation for MS analysis without…

L'équipe Grange/Geigl a récemment publié un châpitre d'ouvrage dans Microbial Environmental Genomics (Part of the Methods in Molecular Biology book series (MIMB,volume 2605) Analysis of Ancient Microbial DNA Abstract The development of next-generation sequencing has led to a breakthrough in the analysis of ancient genomes, and the subsequent genomic analyses of ancient human skeletal remains have revolutionized…

L'équipe Ladoux/Mège publie un nouvel article dans Biomaterials   Bioengineering a miniaturized in vitro 3D myotube contraction monitoring chip to model muscular dystrophies   Abstract Quantification of skeletal muscle functional contraction is essential to assess the outcomes of therapeutic procedures for neuromuscular disorders. Muscle three-dimensional “Organ-on-chip” models usually require a substantial amount of biological material, which rarely…