General information
Offer title : Postdoc in biology on cell cycle control in oocytes (M/F) (H/F)
Reference : UMR7592-KATWAS-003
Number of position : 1
Workplace : PARIS 13
Date of publication : 27 January 2025
Type of Contract : Researcher in FTC
Contract Period : 24 months
Expected date of employment : 7 April 2025
Proportion of work : Full Time
Remuneration : depending on experience, from 4291, 70 € to 4633,50 € before taxes /month
Desired level of education : Doctorate
Experience required : 5 to 10 years
Section(s) CN : 22 – Cellular biology, development, evolution-development, reproduction
Apply on the CNRS job portal before February 17th
Missions
Conduct a set of experiments in an autonomous manner as part of a project on the regulation of the cell cycle during the two meiotic divisions, using two model systems, mouse and Xenopus oocytes.
Activities
The candidate will conduct a set of experiments in an autonomous manner, be able to determine a scientific strategy, execute and interpret the experiments, put the results in a figure format, present the results and contribute to the publication of an article. The candidate will also contribute to the smooth running of the laboratory and supervise students as part of their project.
Skills
Knowledge and experience of studying the cell cycle in meiosis, experience in harvesting mouse and Xenopus laevis oocytes before resumption of meiosis, culture of oocytes from two species to study the two meiotic divisions, fixation of oocytes for immuno-staining of mouse oocytes at different stages of meiosis, injection of oocytes (mouse, Xenopus) and real-time microscopy (mouse) or biochemical assays (Xenopus), image treatment, molecular biology, quantifications, statistical analyses, student supervision, writing of a scientific article. Expert knowledge (spoken/written) of english is a must.
Work Context
The host team is interested in the mechanisms of cell division in meiosis, particularly in mouse and Xenopus oocytes. It is currently made up of 3 doctoral students, 3 engineering assistants, 3 researchers and a lecturer. Bachelor’s and master’s students are welcomed all year round.
The activity is carried out within the Jacques Monod Institute, which is a joint CNRS – Paris Diderot University research unit, of around 250 people and 23 nationalities. The IJM is housed in a recent University building on the Paris Rive Gauche campus located in the 13th arrondissement of Paris and accessible by all means of transport (Metro 14, RER C, Tramway T3, bus 62 and 89.. .).
The necessary equipment is on site, among others: spinning disk microscope (within the team), systems for super resolution (in the institute), microinjectors and microscopy stations for harvesting and injecting mouse and Xenopus oocytes, equipment for biochemistry and molecular biology, adapted computers, etc.
Constraints and risks
No specific constraints or risks