L’équipe Veitia a publié un nouvel article dans Trends in Genetics :
Emerging links between phase separation and transcription factor haploinsufficiency
Résumé :
Recent studies have addressed the relevance of phase separation, by which membrane-less compartments are formed within the nucleus, to understand the impact of genetic variants. They highlight unsuspected links between phase separation and haploinsufficiency of transcription factors.
Veitia RA. Emerging links between phase separation and transcription factor haploinsufficiency. Trends Genet. 2024 Oct 26:S0168-9525(24)00235-X. doi: 10.1016/j.tig.2024.10.001. Epub ahead of print. PMID: 39462709.